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Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends

The repair of DNA double-strand breaks (DSBs) is crucial for maintaining genome stability. The Saccharomyces cerevisiae protein Tbf1, which is characterized by a Myb domain and is related to mammalian TRF1 and TRF2, has been proposed to act as a transcriptional activator. Here, we show that Tbf1 and...

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Bibliografiske detaljer
Main Authors: Bonetti, Diego, Anbalagan, Savani, Lucchini, Giovanna, Clerici, Michela, Longhese, Maria Pia
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553383/
https://ncbi.nlm.nih.gov/pubmed/23222485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.327
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