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The Yku70–Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle
DNA double-strand breaks (DSBs) are repaired by non-homologous end joining (NHEJ) or homologous recombination (HR). HR requires 5′ DSB end degradation that occurs in the presence of cyclin-dependent kinase (CDK) activity. Here, we show that a lack of any of the NHEJ proteins Yku (Yku70–Yku80), Lif1...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2515202/ https://ncbi.nlm.nih.gov/pubmed/18600234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.121 |
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