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Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks

The main responder to DNA double-strand breaks (DSBs) in mammals is ataxia telangiectasia mutated (ATM), whereas DSB-induced checkpoint activation in budding yeast seems to depend primarily on the ATM and Rad-3-related (ATR) orthologue Mec1. Here, we show that Saccharomyces cerevisiae Tel1, the ATM...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mantiero, Davide, Clerici, Michela, Lucchini, Giovanna, Longhese, Maria Pia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852765/
https://ncbi.nlm.nih.gov/pubmed/17347674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400911
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