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Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks
The main responder to DNA double-strand breaks (DSBs) in mammals is ataxia telangiectasia mutated (ATM), whereas DSB-induced checkpoint activation in budding yeast seems to depend primarily on the ATM and Rad-3-related (ATR) orthologue Mec1. Here, we show that Saccharomyces cerevisiae Tel1, the ATM...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852765/ https://ncbi.nlm.nih.gov/pubmed/17347674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400911 |
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