Presence of a defect in karyokinesis during megakaryocyte endomitosis

Megakaryocyte is the naturally polyploid cell that gives rise to platelets. Polyploidization occurs by endomitosis, a process corresponding to a late failure of cytokinesis with a backward movement of the daughter cells. Generally, a pure defect in cytokinesis produces a multinucleated cell, but meg...

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Detalhes bibliográficos
Main Authors: Lordier, Larissa, Pan, Jiajia, Naim, Valeria, Jalil, Abdelali, Badirou, Idinath, Rameau, Philippe, Larghero, Jerôme, Debili, Najet, Rosselli, Filippo, Vainchenker, William, Chang, Yunhua
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552921/
https://ncbi.nlm.nih.gov/pubmed/23159853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22712
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