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Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ
In both budding and fission yeast, a large number of ribonucleotides are incorporated into DNA during replication by the major replicative polymerases (Pols α, δ, and ε). They are subsequently removed by RNase H2-dependent repair, which if defective leads to replication stress and genome instability...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552135/ https://ncbi.nlm.nih.gov/pubmed/23245697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.11.006 |
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