Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ

In both budding and fission yeast, a large number of ribonucleotides are incorporated into DNA during replication by the major replicative polymerases (Pols α, δ, and ε). They are subsequently removed by RNase H2-dependent repair, which if defective leads to replication stress and genome instability...

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Bibliographic Details
Main Authors:	Clausen, Anders R., Zhang, Sufang, Burgers, Peter M., Lee, Marietta Y., Kunkel, Thomas A.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3552135/ https://ncbi.nlm.nih.gov/pubmed/23245697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.11.006
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Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ

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