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TLR4 Activation Under Lipotoxic Conditions Leads to Synergistic Macrophage Cell Death Through a TRIF-Dependent Pathway()

Macrophage dysfunction in obesity and diabetes may predispose to the development of diabetic complications such as infection and impaired healing after tissue damage. Saturated fatty acids, such as palmitate, are present at elevated concentrations in the plasma of patients with metabolic disease and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schilling, Joel D., Machkovech, Heather M., He, Li, Diwan, Abhinav, Schaffer, Jean E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552058/
https://ncbi.nlm.nih.gov/pubmed/23275600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202208
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