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TLR4 Activation Under Lipotoxic Conditions Leads to Synergistic Macrophage Cell Death Through a TRIF-Dependent Pathway()
Macrophage dysfunction in obesity and diabetes may predispose to the development of diabetic complications such as infection and impaired healing after tissue damage. Saturated fatty acids, such as palmitate, are present at elevated concentrations in the plasma of patients with metabolic disease and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552058/ https://ncbi.nlm.nih.gov/pubmed/23275600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202208 |
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