लोड हो रहा है...

Inhibition of mTOR reduces lipotoxic cell death in primary macrophages through an autophagy-independent mechanism

Macrophage dysfunction in obesity and diabetes is associated with persistent inflammation and poor wound healing responses. Relevant to these phenotypes, we have previously shown that macrophage activation in a high-fat environment results in cell death via a mechanism that involves lysosome damage....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Leukoc Biol
मुख्य लेखकों: He, Li, Weber, Kassandra J., Diwan, Abhinav, Schilling, Joel D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Leukocyte Biology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069097/
https://ncbi.nlm.nih.gov/pubmed/27312848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1015-463R
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