Inhibition of mTOR reduces lipotoxic cell death in primary macrophages through an autophagy-independent mechanism

Macrophage dysfunction in obesity and diabetes is associated with persistent inflammation and poor wound healing responses. Relevant to these phenotypes, we have previously shown that macrophage activation in a high-fat environment results in cell death via a mechanism that involves lysosome damage....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: He, Li, Weber, Kassandra J., Diwan, Abhinav, Schilling, Joel D.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2016
Fag:
Inflammation, Extracellular Mediators, & Effector Molecules
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069097/
https://ncbi.nlm.nih.gov/pubmed/27312848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1015-463R
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker