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Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages

Macrophages play a key role in host defense and in tissue repair after injury. Emerging evidence suggests that macrophage dysfunction in states of lipid excess can contribute to the development of insulin resistance and may underlie inflammatory complications of diabetes. Ceramides are sphingolipids...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schilling, Joel D., Machkovech, Heather M., He, Li, Sidhu, Rohini, Fujiwara, Hideji, Weber, Kassandra, Ory, Daniel S., Schaffer, Jean E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561515/
https://ncbi.nlm.nih.gov/pubmed/23250746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419978
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