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Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages
Macrophages play a key role in host defense and in tissue repair after injury. Emerging evidence suggests that macrophage dysfunction in states of lipid excess can contribute to the development of insulin resistance and may underlie inflammatory complications of diabetes. Ceramides are sphingolipids...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561515/ https://ncbi.nlm.nih.gov/pubmed/23250746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419978 |
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