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Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism

Improving the control of energy homeostasis can lower cardiovascular risk in metabolically compromised individuals. To identify new regulators of whole-body energy control, we conducted a high-throughput screen in transgenic reporter zebrafish for small molecules that modulate the expression of the...

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Detalhes bibliográficos
Main Authors: Gut, Philipp, Baeza-Raja, Bernat, Andersson, Olov, Hasenkamp, Laura, Hsiao, Joseph, Hesselson, Daniel, Akassoglou, Katerina, Verdin, Eric, Hirschey, Matthew D., Stainier, Didier Y.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552031/
https://ncbi.nlm.nih.gov/pubmed/23201900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1136
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