Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation

Inducing beta-cell mass expansion in diabetic patients with the aim to restore glucose homeostasis is a promising therapeutic strategy. Although several in vitro studies have been carried out to identify modulators of beta-cell mass expansion, restoring endogenous beta-cell mass in vivo has yet to b...

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Main Authors: Tsuji, Naoki, Ninov, Nikolay, Delawary, Mina, Osman, Sahar, Roh, Alex S., Gut, Philipp, Stainier, Didier Y. R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130527/
https://ncbi.nlm.nih.gov/pubmed/25117518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104112
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