Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling

Previous studies have identified Notch as a key regulator of hematopoietic stem cell (HSC) development, but the underlying downstream mechanisms remain unknown. The Notch target Hes1 is widely expressed in the aortic endothelium and hematopoietic clusters, though Hes1-deficient mice show no overt he...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Guiu, Jordi, Shimizu, Ritsuko, D’Altri, Teresa, Fraser, Stuart T., Hatakeyama, Jun, Bresnick, Emery H., Kageyama, Ryoichiro, Dzierzak, Elaine, Yamamoto, Masayuki, Espinosa, Lluis, Bigas, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549704/
https://ncbi.nlm.nih.gov/pubmed/23267012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120993
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk