Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb

BACKGROUND: The receptor for the cytokine TWEAK (TweakR) is a cell surface member of the tumor necrosis factor receptor superfamily with diverse biological roles. TNFRSF family members are appealing therapeutic targets in oncology due to their aberrant expression and function in tumor cells. The goa...

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Autors principals: Chao, Debra T., Su, Mian, Tanlimco, Sonia, Sho, Mien, Choi, Donghee, Fox, Mel, Ye, Shiming, Hsi, Eric D., Durkin, Lisa, Yin, Johnny, Zhang, Yongke, Kim, Han, Starling, Gary C., Culp, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549414/
https://ncbi.nlm.nih.gov/pubmed/23073510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-012-1332-x
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