Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR

TweakR is a TNF receptor family member, whose natural ligand is the multifunctional cytokine TWEAK. The growth inhibitory activity observed following TweakR stimulation in certain cancer cell lines and the overexpression of TweakR in many solid tumor types led to the development of enavatuzumab (PDL...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Purcell, James W., Kim, Han K., Tanlimco, Sonia G., Doan, Minhtam, Fox, Melvin, Lambert, Peter, Chao, Debra T., Sho, Mien, Wilson, Keith E., Starling, Gary C., Culp, Patricia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884146/
https://ncbi.nlm.nih.gov/pubmed/24409185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00505
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky