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Evolutionary Conservation of Nkx2.5 Autoregulation in the Second Heart Field
The cardiac homeobox gene Nkx2.5 plays a key and dosage-sensitive role in the differentiation of outflow tract and right ventricle from progenitors of the second heart field (SHF) and Nkx2.5 mutation is strongly associated with human outflow tract congenital heart disease (OFT CHD). Therefore defini...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549048/ https://ncbi.nlm.nih.gov/pubmed/23165293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.11.007 |
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