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Second Heart Field-specific expression of Nkx2-5 requires promoter proximal interaction with Srf

The cardiac homeobox transcription factor Nkx2-5 is a major determinant of cardiac identity and cardiac morphogenesis. Nkx2-5 operates as part of a complex and mutually reinforcing network of early transcription factors of the homeobox, GATA zinc finger and MADS domain families to initiate the progr...

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Dettagli Bibliografici
Pubblicato in:Mech Dev
Autori principali: Clark, Christopher D., Lee, Kyu-Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525830/
https://ncbi.nlm.nih.gov/pubmed/32450132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2020.103615
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