Evolutionary Conservation of Nkx2.5 Autoregulation in the Second Heart Field

The cardiac homeobox gene Nkx2.5 plays a key and dosage-sensitive role in the differentiation of outflow tract and right ventricle from progenitors of the second heart field (SHF) and Nkx2.5 mutation is strongly associated with human outflow tract congenital heart disease (OFT CHD). Therefore defini...

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Detaylı Bibliyografya
Asıl Yazarlar: Clark, Christopher D., Zhang, Boding, Lee, Benjamin, Evans, Samuel I., Lassar, Andrew B., Lee, Kyu-Ho
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549048/
https://ncbi.nlm.nih.gov/pubmed/23165293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.11.007
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