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Multiple cis-elements and trans-acting factors regulate dynamic spatio-temporal transcription of let-7 in C. elegans
The let-7 microRNA (miRNA) is highly conserved across animal phyla and generally regulates cellular differentiation and developmental timing pathways. In C. elegans, the mature let-7 miRNA starts to accumulate in the last stages of larval development where it directs cellular differentiation program...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548979/ https://ncbi.nlm.nih.gov/pubmed/23201578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.11.021 |
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