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Multiple cis-elements and trans-acting factors regulate dynamic spatio-temporal transcription of let-7 in C. elegans

The let-7 microRNA (miRNA) is highly conserved across animal phyla and generally regulates cellular differentiation and developmental timing pathways. In C. elegans, the mature let-7 miRNA starts to accumulate in the last stages of larval development where it directs cellular differentiation program...

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Bibliografski detalji
Glavni autori: Kai, Zoya S., Finnegan, Emily F., Huang, Stacey, Pasquinelli, Amy E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548979/
https://ncbi.nlm.nih.gov/pubmed/23201578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.11.021
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