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Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer

Enhanced bone destruction is a hallmark of various carcinomas such as breast cancer, where osteolytic bone metastasis is associated with increased morbidity and mortality. Immune cells contribute to osteolysis in cancer growth but the factors contributing to aggressive bone destruction are not well...

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Hlavní autoři: Sawant, Anandi, Deshane, Jessy, Jules, Joel, Lee, Carnella M., Harris, Brittney A., Feng, Xu, Ponnazhagan, Selvarangan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548966/
https://ncbi.nlm.nih.gov/pubmed/23243021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2202
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