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Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer

Enhanced bone destruction is a hallmark of various carcinomas such as breast cancer, where osteolytic bone metastasis is associated with increased morbidity and mortality. Immune cells contribute to osteolysis in cancer growth but the factors contributing to aggressive bone destruction are not well...

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Autors principals: Sawant, Anandi, Deshane, Jessy, Jules, Joel, Lee, Carnella M., Harris, Brittney A., Feng, Xu, Ponnazhagan, Selvarangan
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548966/
https://ncbi.nlm.nih.gov/pubmed/23243021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2202
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