Prostate cancer-derived cathelicidin-related antimicrobial peptide facilitates macrophage differentiation and polarization of immature myeloid progenitors to protumorigenic macrophages

BACKGROUND: A growing body of evidence indicates a positive correlation between expression of human antimicrobial peptide leucin leucin 37 (LL-37) and progression of epithelial cancers, including prostate cancer (PCa). Although the molecular mechanisms for this correlation has not yet been elucidate...

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Detalhes bibliográficos
Publicado no:Prostate
Principais autores: Cha, Ha-Ram, Lee, Joo Hyoung, Hensel, Jonathan A., Sawant, Anandi B., Davis, Brittney H., Lee, Carnellia M., Deshane, Jessy S., Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551898/
https://ncbi.nlm.nih.gov/pubmed/26856684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23155
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