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Myeloid-derived suppressor cells as a novel target for the control of osteolytic bone disease
Myeloid-derived suppressor cells (MDSC) from mice bearing bone metastases differentiate into functional osteoclasts in vitro and in vivo, through a signaling pathway that relies on nitric oxide. In addition, MDSC-targeting drugs have been shown to robustly inhibit osteolysis. Thus, MDSC stand out as...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667900/ https://ncbi.nlm.nih.gov/pubmed/23762794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24064 |
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