Mast Cells Express 11β-hydroxysteroid Dehydrogenase Type 1: A Role in Restraining Mast Cell Degranulation

Mast cells are key initiators of allergic, anaphylactic and inflammatory reactions, producing mediators that affect vascular permeability, angiogenesis and fibrosis. Glucocorticoid pharmacotherapy reduces mast cell number, maturation and activation but effects at physiological levels are unknown. Wi...

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Detalhes bibliográficos
Main Authors: Coutinho, Agnes E., Brown, Jeremy K., Yang, Fu, Brownstein, David G., Gray, Mohini, Seckl, Jonathan R., Savill, John S., Chapman, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548897/
https://ncbi.nlm.nih.gov/pubmed/23349944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054640
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