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Variants in the 15q24/25 Locus Associate with Lung Function Decline in Active Smokers

Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of nAChR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohamed Hoesein, Firdaus A. A., Wauters, Els, Janssens, Wim, Groen, Harry J. M., Smolonska, Joanna, Wijmenga, Cisca, Postma, Dirkje S., Boezen, H. Marike, De Jong, Pim A., Decramer, Marc, Lammers, Jan-Willem J., Lambrechts, Diether, Zanen, Pieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548843/
https://ncbi.nlm.nih.gov/pubmed/23349703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053219
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