Variants in the 15q24/25 Locus Associate with Lung Function Decline in Active Smokers

Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of nAChR...

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Main Authors: Mohamed Hoesein, Firdaus A. A., Wauters, Els, Janssens, Wim, Groen, Harry J. M., Smolonska, Joanna, Wijmenga, Cisca, Postma, Dirkje S., Boezen, H. Marike, De Jong, Pim A., Decramer, Marc, Lammers, Jan-Willem J., Lambrechts, Diether, Zanen, Pieter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548843/
https://ncbi.nlm.nih.gov/pubmed/23349703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053219
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