Dissecting genetics for chronic mucus hypersecretion in smokers with and without COPD: genome wide analysis on mucus hypersecretion

BACKGROUND: Smoking is a notorious risk factor for chronic mucus hypersecretion (CMH). CMH frequently occurs in Chronic Obstructive Pulmonary Disease (COPD). The question arises whether the same single nucleotide polymorphisms (SNPs) are related to CMH in smokers with and without COPD. METHODS: We p...

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Bibliografiset tiedot
Julkaisussa:Eur Respir J
Päätekijät: Dijkstra, Akkelies E., Boezen, H. Marike, van den Berge, Maarten, Vonk, Judith M., Hiemstra, Pieter S., Barr, R. Graham, Burkart, Kirsten M., Manichaikul, Ani, Pottinger, Tess D., Silverman, Edwin K., Cho, Michael H., Crapo, James D., Beaty, Terri H., Bakke, Per, Gulsvik, Amund, Lomas, David A., Bossé, Yohan, Nickle, David C., Paré, Peter D., de Koning, Harry J., Lammers, Jan-Willem, Zanen, Pieter, Smolonska, Joanna, Wijmenga, Ciska, Brandsma, Corry-Anke, Groen, Harry J.M., Postma, Dirkje S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498483/
https://ncbi.nlm.nih.gov/pubmed/25234806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00093314
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