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Conopeptide ρ-TIA Defines a New Allosteric Site on the Extracellular Surface of the α(1B)-Adrenoceptor
The G protein-coupled receptor (GPCR) superfamily is an important drug target that includes over 1000 membrane receptors that functionally couple extracellular stimuli to intracellular effectors. Despite the potential of extracellular surface (ECS) residues in GPCRs to interact with subtype-specific...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548491/ https://ncbi.nlm.nih.gov/pubmed/23184947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430785 |
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