Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

Cone snails are a diverse group of predatory marine invertebrates that deploy remarkably complex venoms to rapidly paralyse worm, mollusc or fish prey. ω-Conotoxins are neurotoxic peptides from cone snail venoms that inhibit Ca(v)2.2 voltage-gated calcium channel, demonstrating potential for pain ma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sousa, Silmara R., McArthur, Jeffrey R., Brust, Andreas, Bhola, Rebecca F., Rosengren, K. Johan, Ragnarsson, Lotten, Dutertre, Sebastien, Alewood, Paul F., Christie, Macdonald J., Adams, David J., Vetter, Irina, Lewis, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128854/
https://ncbi.nlm.nih.gov/pubmed/30194442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31245-4
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