The IRE1α-XBP1 Pathway Positively Regulates Parathyroid Hormone (PTH)/PTH-related Peptide Receptor Expression and Is Involved in PTH-induced Osteoclastogenesis

To address the “endoplasmic reticulum stress” triggered by the burden of protein synthesis, the unfolded protein response is induced during osteoblast differentiation. In this study, we show that the transcription of parathyroid hormone (PTH)/PTH-related peptide receptor (PTH1R) is regulated by one...

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Autori principali: Tohmonda, Takahide, Yoda, Masaki, Mizuochi, Hiroshi, Morioka, Hideo, Matsumoto, Morio, Urano, Fumihiko, Toyama, Yoshiaki, Horiuchi, Keisuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548479/
https://ncbi.nlm.nih.gov/pubmed/23235147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.424606
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