Epidermal Growth Factor Promotes Protein Degradation of Epithelial Protein Lost in Neoplasm (EPLIN), a Putative Metastasis Suppressor, during Epithelial-mesenchymal Transition

Aberrant expression of EGF receptors has been associated with hormone-refractory and metastatic prostate cancer (PCa). However, the molecular mechanism for EGF signaling in promoting PCa metastasis remains elusive. Using experimental models of PCa metastasis, we demonstrated that EGF could induce ro...

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Detalhes bibliográficos
Main Authors: Zhang, Shumin, Wang, Xu, Iqbal, Shareen, Wang, Yanru, Osunkoya, Adeboye O., Chen, Zhengjia, Chen, Zhuo, Shin, Dong M., Yuan, Hongwei, Wang, Yongqiang A., Zhau, Haiyen E., Chung, Leland W. K., Ritenour, Chad, Kucuk, Omer, Wu, Daqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548460/
https://ncbi.nlm.nih.gov/pubmed/23188829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438341
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