Epidermal Growth Factor Promotes Protein Degradation of Epithelial Protein Lost in Neoplasm (EPLIN), a Putative Metastasis Suppressor, during Epithelial-mesenchymal Transition

Aberrant expression of EGF receptors has been associated with hormone-refractory and metastatic prostate cancer (PCa). However, the molecular mechanism for EGF signaling in promoting PCa metastasis remains elusive. Using experimental models of PCa metastasis, we demonstrated that EGF could induce ro...

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主要な著者: Zhang, Shumin, Wang, Xu, Iqbal, Shareen, Wang, Yanru, Osunkoya, Adeboye O., Chen, Zhengjia, Chen, Zhuo, Shin, Dong M., Yuan, Hongwei, Wang, Yongqiang A., Zhau, Haiyen E., Chung, Leland W. K., Ritenour, Chad, Kucuk, Omer, Wu, Daqing
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
Molecular Bases of Disease
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548460/
https://ncbi.nlm.nih.gov/pubmed/23188829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438341
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