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Intracellular delivery of doxorubicin encapsulated in novel pH-responsive chitosan/heparin nanocapsules

A novel polyelectrolyte nanocapsule system composed of biopolymers, chitosan and heparin has been fabricated by the layer-by-layer technique on silica nanoparticles followed by dissolution of the silica core. The nanocapsules were of the size range 200 ± 20 nm and loaded with the positively charged...

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Detalhes bibliográficos
Main Authors: Thomas, Midhun B, Radhakrishnan, Krishna, Gnanadhas, Divya P, Chakravortty, Dipshikha, Raichur, Ashok M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548417/
https://ncbi.nlm.nih.gov/pubmed/23345974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S37737
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