Intracellular Delivery and Antibacterial Activity of Gentamicin Encapsulated in pH-Sensitive Liposomes

Cell membranes are relatively impermeable to the antibiotic gentamicin, a factor that, along with the toxicity of gentamicin, precludes its use against many important intracellular bacterial infections. Liposomal encapsulation of this drug was used in order to achieve intracellular antibiotic delive...

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Main Authors: Lutwyche, Peter, Cordeiro, Carol, Wiseman, David J., St-Louis, Maryse, Uh, Mitchell, Hope, Michael J., Webb, Murray S., Finlay, B. Brett
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Susceptibility
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC105873/
https://ncbi.nlm.nih.gov/pubmed/9756749
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