Intracellular Delivery and Antibacterial Activity of Gentamicin Encapsulated in pH-Sensitive Liposomes

Cell membranes are relatively impermeable to the antibiotic gentamicin, a factor that, along with the toxicity of gentamicin, precludes its use against many important intracellular bacterial infections. Liposomal encapsulation of this drug was used in order to achieve intracellular antibiotic delive...

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Hauptverfasser: Lutwyche, Peter, Cordeiro, Carol, Wiseman, David J., St-Louis, Maryse, Uh, Mitchell, Hope, Michael J., Webb, Murray S., Finlay, B. Brett
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105873/
https://ncbi.nlm.nih.gov/pubmed/9756749
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