Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against an in vivo intracellular Salmonella model

Pluronic based core-shell nanostructures encapsulating gentamicin were designed in this study. Block copolymers of (PAA(−+)Na-b-(PEO-b-PPO-b-PEO)-b-PAA(−+)Na) were blended with PAA(−) Na(+) and complexed with the polycationic antibiotic gentamicin to form nanostructures. Synthesized nanostructures h...

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Main Authors: Ranjan, Ashish, Pothayee, Nikorn, Seleem, Mohammed N, Tyler, Ronald D, Brenseke, Bonnie, Sriranganathan, Nammalwar, Riffle, Judy S, Kasimanickam, Ramanathan
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2009
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802042/
https://ncbi.nlm.nih.gov/pubmed/20054433
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