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Protein Nanocapsules Containing Doxorubicin as a pH-Responsive Delivery System

The E2 component of pyruvate dehydrogenase has been engineered to form a caged, hollow dodecahedral protein assembly, and we have examined the feasibility of this scaffold to be used as a drug delivery system by introducing cysteines to the internal cavity (D381C). Fluorescent dye Alexa Fluor 532 (A...

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Bibliografiske detaljer
Main Authors: Ren, Dongmei, Kratz, Felix, Wang, Szu-Wen
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118673/
https://ncbi.nlm.nih.gov/pubmed/21456086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201002242
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