Engineering of Doxorubicin-Encapsulating and TRAIL-Conjugated Poly(RGD) Proteinoid Nanocapsules for Drug Delivery Applications

Proteinoids are non-toxic biodegradable polymers prepared by thermal step-growth polymerization of amino acids. Here, P(RGD) proteinoids and proteinoid nanocapsules (NCs) based on D-arginine, glycine, and L-aspartic acid were synthesized and characterized for targeted tumor therapy. Doxorubicin (Dox...

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Gepubliceerd in:Polymers (Basel)
Hoofdauteurs: Hadad, Elad, Rudnick-Glick, Safra, Itzhaki, Ella, Avivi, Matan Y., Grinberg, Igor, Elias, Yuval, Margel, Shlomo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765502/
https://ncbi.nlm.nih.gov/pubmed/33339090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12122996
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