Engineering of Doxorubicin-Encapsulating and TRAIL-Conjugated Poly(RGD) Proteinoid Nanocapsules for Drug Delivery Applications

Proteinoids are non-toxic biodegradable polymers prepared by thermal step-growth polymerization of amino acids. Here, P(RGD) proteinoids and proteinoid nanocapsules (NCs) based on D-arginine, glycine, and L-aspartic acid were synthesized and characterized for targeted tumor therapy. Doxorubicin (Dox...

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Bibliografiske detaljer
Udgivet i:Polymers (Basel)
Main Authors: Hadad, Elad, Rudnick-Glick, Safra, Itzhaki, Ella, Avivi, Matan Y., Grinberg, Igor, Elias, Yuval, Margel, Shlomo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765502/
https://ncbi.nlm.nih.gov/pubmed/33339090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12122996
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