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Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

The Nonhomologous end joining pathway is essential for efficient repair of chromosome double strand breaks. This pathway consequently plays a key role in cellular resistance to break-inducing exogenous agents, as well as in the developmentally-programmed recombinations that are required for adaptive...

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Autori principali: Strande, Natasha Tiffany, Waters, Crystal Ann, Ramsden, Dale A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547747/
https://ncbi.nlm.nih.gov/pubmed/23276302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-3-10
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