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Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids

Prolonged exposure of isolated islets to supraphysiologic concentrations of palmitate decreases insulin gene expression in the presence of elevated glucose levels. This study was designed to determine whether or not this phenomenon is associated with a glucose-dependent increase in esterification of...

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Detaylı Bibliyografya
Asıl Yazarlar: Briaud, Isabelle, Harmon, Jamie S., Kelpe, Cynthia L., Segu, Venkatesh Babu G., Poitout, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547289/
https://ncbi.nlm.nih.gov/pubmed/11272142
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