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Glucocorticoid Receptor and Histone Deacetylase–2 Mediate Dexamethasone-Induced Repression of MUC5AC Gene Expression
Airway occlusion in obstructive airway diseases is caused in part by the overproduction of secretory mucin glycoproteins through the up-regulation of mucin (MUC) genes by inflammatory mediators. Some pharmacological agents, including the glucocorticoid dexamethasone (Dex), repress mucin concentratio...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Thoracic Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547101/ https://ncbi.nlm.nih.gov/pubmed/22798432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0009OC |
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