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Mitochondrial and Secretory Human Cytomegalovirus UL37 Proteins Traffic into Mitochondrion-Associated Membranes of Human Cells

The human cytomegalovirus (HCMV) UL37 exon 1 protein (pUL37x1), also known as vMIA, is the predominant UL37 isoform during permissive infection. pUL37x1 is a potent antiapoptotic protein, which prevents cytochrome c release from mitochondria. The UL37x1 NH(2)-terminal bipartite localization signal,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bozidis, Petros, Williamson, Chad D., Colberg-Poley, Anamaris M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258971/
https://ncbi.nlm.nih.gov/pubmed/18199645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02456-07
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