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Processing of Human Cytomegalovirus UL37 Mutant Glycoproteins in the Endoplasmic Reticulum Lumen prior to Mitochondrial Importation

The human cytomegalovirus (HCMV) UL37 glycoprotein (gpUL37) is internally cleaved and its products divergently traffic to mitochondria or are retained in the secretory pathway. To define the requirements for gpUL37 cleavage, residues −1 and −3 of the consensus endoplasmic reticulum (ER) signal pepti...

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Auteurs principaux: Mavinakere, Manohara S., Williamson, Chad D., Goldmacher, Victor S., Colberg-Poley, Anamaris M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489043/
https://ncbi.nlm.nih.gov/pubmed/16809283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00492-06
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