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Processing of Human Cytomegalovirus UL37 Mutant Glycoproteins in the Endoplasmic Reticulum Lumen prior to Mitochondrial Importation

The human cytomegalovirus (HCMV) UL37 glycoprotein (gpUL37) is internally cleaved and its products divergently traffic to mitochondria or are retained in the secretory pathway. To define the requirements for gpUL37 cleavage, residues −1 and −3 of the consensus endoplasmic reticulum (ER) signal pepti...

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Detalhes bibliográficos
Main Authors: Mavinakere, Manohara S., Williamson, Chad D., Goldmacher, Victor S., Colberg-Poley, Anamaris M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489043/
https://ncbi.nlm.nih.gov/pubmed/16809283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00492-06
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