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Human cytomegalovirus pUL37x1 induces the release of endoplasmic reticulum calcium stores

The human CMV UL37x1-encoded protein, also known as the viral mitochondria-localized inhibitor of apoptosis, traffics to the endoplasmic reticulum and mitochondria of infected cells. It induces the fragmentation of mitochondria and blocks apoptosis. We demonstrate that UL37x1 protein mobilizes Ca(2+...

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Detalhes bibliográficos
Main Authors: Sharon-Friling, Ronit, Goodhouse, Joseph, Colberg-Poley, Anamaris M., Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748185/
https://ncbi.nlm.nih.gov/pubmed/17135350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609353103
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