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Dexamethasone-Mediated Repression of MUC5AC Gene Expression in Human Lung Epithelial Cells

Glucocorticoids regulate gene expression via binding of the ligand-activated glucocorticoid receptor (GR) to glucocorticoid-responsive elements (GRE) in target gene promoters. The MUC5AC gene, which encodes the protein backbone of an abundant secreted airway mucin, has several putative GRE cis-eleme...

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Detalhes bibliográficos
Main Authors: Chen, Yajun, Nickola, Tracey J., DiFronzo, Nancy L., Colberg-Poley, Anamaris M., Rose, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644199/
https://ncbi.nlm.nih.gov/pubmed/16239644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0176OC
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