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Dexamethasone modulation of MUC5AC and MUC2 gene expression in a generalized model of middle ear inflammation

OBJECTIVE: To examine the effect of dexamethasone on basal and pro-inflammatory cytokines induced gel forming mucin expression in human middle ear epithelium culture (HMEEC-1). METHODS: HMEEC-1 was exposed to pro-inflammatory cytokines, TNF-α and IL-1β to identify optimal mucin induction. The HMEEC-...

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Detalhes bibliográficos
Publicado no:Laryngoscope
Main Authors: Kerschner, Joseph E., Khampang, Pawjai, Hong, Wenzhou
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854820/
https://ncbi.nlm.nih.gov/pubmed/26525635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.25762
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