Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model

BACKGROUND: Progressive accumulation of α-synuclein (α-Syn) protein in different brain regions is a hallmark of synucleinopathic diseases, such as Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy. α-Syn transgenic mouse models have been developed to investigate the effects...

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Main Authors: Amschl, David, Neddens, Jörg, Havas, Daniel, Flunkert, Stefanie, Rabl, Roland, Römer, Heinrich, Rockenstein, Edward, Masliah, Eliezer, Windisch, Manfred, Hutter-Paier, Birgit
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546911/
https://ncbi.nlm.nih.gov/pubmed/23302418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-6
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