Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice

BACKGROUND: Synucleinopathies such as Parkinson’s disease or multiple system atrophy are characterized by Lewy bodies in distinct brain areas. These aggregates are mainly formed by α-synuclein inclusions, a protein crucial for synaptic functions in the healthy brain. Transgenic animal models of synu...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Rabl, R., Breitschaedel, C., Flunkert, S., Duller, S., Amschl, D., Neddens, J., Niederkofler, V., Rockenstein, E., Masliah, E., Roemer, H., Hutter-Paier, B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282838/
https://ncbi.nlm.nih.gov/pubmed/28143405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0341-8
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